

Primary recommendation: keep essential prescription items in cabin carry-on; place noncritical spares inside hold baggage only after confirming airline and destination regulations. Cabin storage reduces loss and temperature exposure, while hold storage increases risk of damage, theft, or seizure at international borders.
Follow these concrete steps before departure: pack medicines in original pharmacy-labeled containers, carry a copy of the prescription and a signed physician letter stating medical need and generic names, limit quantities to a reasonable amount (commonly a 30–90 day supply depending on destination), and photograph each item and documentation. For liquids or injectables, note that US screening rules permit containers larger than 3.4 oz (100 ml) for medical use but these items must be declared at the checkpoint; keep them accessible for inspection.
Controlled substances require extra paperwork: obtain an export/import permit when required, verify national lists of prohibited compounds (examples of strict jurisdictions include Singapore, UAE and Japan for certain opioids and pseudoephedrine-containing products), and contact the nearest embassy or national health authority at least two weeks prior to travel to request written confirmation if needed.
Temperature-sensitive therapy (insulin, biologics): store in cabin inside an insulated case with gel coolants that do not freeze products; avoid checked placement because baggage holds are subject to extreme temperature swings and delayed retrieval. Request pre-boarding storage assistance from the airline crew for refrigeration options only when airline policy explicitly permits in-flight storage.
When stowing duplicates in hold baggage, seal containers in waterproof bags, use cushioning to prevent crushing, split supplies across separate bags to reduce total loss risk, and leave a small emergency dose in the cabin bag. Verify airline carry-on allowances and customs import limits via airline website and official government portals at least 72 hours before travel.
Which airlines and airports allow prescription medicines in hold baggage – where to verify policy details
Recommendation: carry essential prescription medicines in cabin carry-on; place backup supplies in the aircraft hold only after verifying carrier and airport regulations and documentation requirements.
Airline-specific guidance
- Delta Air Lines – Prescription medicines permitted in cabin and aircraft hold; liquids over 100 ml allowed in cabin when declared as medically necessary at security; consult Delta’s Medical & Baggage pages for quantity limits and required paperwork.
- American Airlines – Supports carriage of prescription medicines in both cabin and hold; controlled substances require original prescription labeling and possibly advance notice for international flights; refer to American’s Special Baggage/Medical FAQ.
- United Airlines – Encourages storing critical doses in cabin; spare supplies may be stowed in hold if packed securely; United’s Dangerous Goods and Medical Travel pages list documentation and liquid exceptions.
- British Airways – Allows prescription medicines in cabin and hold; liquids exemption applies for prescribed liquids if accompanied by supporting documentation; consult BA’s baggage and medical information online.
- Lufthansa / Air France / KLM – Each carrier permits prescription medicines but differs on quantity limits, accepted documentation and declaration procedure at security; review the carrier-specific “medical items” section before departure.
- Emirates / Qatar Airways / Singapore Airlines – International carriers accept prescription medicines but often require prescriptions in English and may require prior approval for controlled drugs; inspect the airline’s health or special assistance pages.
Where to verify rules (step-by-step)
- Airline official site – Search the carrier’s baggage, medical items or dangerous-goods pages for exact wording on permitted items, liquid exemptions, documentation and advance-notice procedures.
- Airport authority – Review the departure and transit airport’s security pages for local screening rules and permitted-item lists; major hubs sometimes impose additional transit constraints. For non-medical travel gear, consider best outdoor chair with umbrella.
- National regulators – Consult TSA.gov (United States), CAA (UK), EASA (European Union), CASA (Australia) or equivalent authority for official guidance on transport of prescription medicines, liquid limits and screening protocols.
- Customs & controlled substances – Check destination and transit-country customs sites for import restrictions, required permits or notification procedures for controlled drugs; failure to carry paperwork can lead to seizure or fines.
- Proof in writing – When policy ambiguity affects planned routing, request written confirmation from the carrier (email or support ticket) specifying allowed quantities, required labels and declaration steps; retain screenshots or PDFs during travel.
Practical checklist before departure: confirm carrier policy, obtain original prescription labels, secure a doctor’s letter in English if travelling internationally, pack critical doses in the cabin carry-on, and print regulatory pages or confirmations for border officers and security staff.
How to package pills, inhalers and liquid medicines for hold baggage to avoid spills and damage
Keep solid tablets in original pharmacy-labeled bottles whenever possible; place each bottle inside a heavy-duty resealable plastic bag, add a silica gel packet, then position inside a small hard-sided case cushioned by clothing or foam.
Pills and tablets
Transfer only duplicates to daily pill organisers; retain at least one original container per drug for identification. For fragile tablets, keep blister strips intact and slip into a zip-seal bag. Use desiccant packs for hygroscopic formulations. For high-value or brittle capsules, place a 1–2 cm layer of closed-cell foam beneath and around the container inside a rigid box (Pelican-style or small hard travel case).
Inhalers and liquid formulations
Keep pressurised inhalers in their original box when feasible. Wrap nozzle and cap with a short length of medical-grade ParaFilm or waterproof tape, then double-bag in heavy zip-seal plastic; place upright between soft garments inside a rigid container. For oral liquids and syrups, apply a strip of Parafilm or put a piece of cling film over the bottle opening before screwing the cap on, then seal in two nested zip-seal bags with absorbent paper towel between layers. Store glass bottles in a padded, upright position inside a hard toiletry case; vacuum-seal pouches are acceptable for extra leak protection but avoid crushing glass.
Temperature-sensitive products (example: insulin) require refrigerated storage (2–8 °C) and therefore should remain in cabin baggage; avoid stowing such items in the cargo hold. Expect possible exposure to low or high temperatures in hold compartments–plan packaging accordingly and include cold packs inside an insulated pouch for short duration exposure only.
Label every item with drug name (generic and brand), dose, prescribing clinician and a printed prescription or clinician note. Place that documentation and a medication list in a separate waterproof envelope inside the same protective case. For added security, keep the primary hard case inside a sturdy carry bag such as a best backpack with hip belt, or inside checked baggage compartments padded by clothing to reduce impact damage.
Prescription labels, original containers and doctor’s letters for stowed/hold baggage
Keep pharmacy labels intact on original containers and carry a physician’s signed letter on clinic or hospital letterhead listing drug names, strengths, dosages, total quantity and medical justification.
- Required label fields
- Full legal name matching passport or ID
- Drug name(s): brand and generic
- Strength (e.g., 10 mg, 100 IU/mL) and dosage form (tablet, capsule, inhaler, injection)
- Quantity dispensed and date of dispensing
- Prescriber’s name and contact number; prescriber registration/license number when available
- Pharmacy name, phone number and prescription/dispense number
- Lot or batch number where present (important for injectables and biologics)
- Original container guidance
- Retain manufacturer box or pharmacy bottle for each product; do not transfer into pill organizers for stowage
- Keep blister packs sealed with visible lot and expiry information
- Insulin pens, syringes and prefilled devices: keep in original packaging showing serial/lot numbers and manufacturer label
- For temperature-sensitive products, include manufacturer/pharmacy temperature instructions and a note from prescriber about storage needs
- Doctor’s letter: required content
- Official clinic/hospital letterhead, printed date and original signature (digital signature acceptable only if widely accepted at destination)
- Patient full legal name and passport number
- List of medicines by generic and brand name, strength, route of administration and usual dosing schedule
- Total quantity carried and duration of therapy covered (e.g., 90-day supply)
- Medical indication or ICD-10 code when available
- Statement that products are for personal medical use and cannot be substituted safely
- Prescriber’s contact details, professional registration/license number and stamp where applicable
- Controlled substances and larger quantities
- Include prescriber DEA or national controlled-substance registration number for U.S.-origin prescriptions
- Add a justification paragraph specifying medical need and travel dates; list exact milligram totals and number of units
- Obtain embassy or consulate guidance and, if required, an apostille/notarization or pre-approval letter from destination authorities
- Copies, formats and translations
- Carry two paper copies of the prescription labels and doctor’s letter; store one set in hand luggage and one in hold baggage
- Keep encrypted digital copies (PDF) offline on a phone and on cloud storage accessible if requested
- Translate doctor’s letter into the destination language for non-English countries when requested by local customs or health authorities
- Quick checklist before departure
- All meds in original labeled containers
- Doctor’s letter on letterhead, signed and dated
- Copies and digital backups created
- Controlled-substance paperwork (registration/DEA/license) included if applicable
- Contact details for prescriber and dispensing pharmacy visible
Rules and permits for controlled substances and narcotics in hold baggage
Declare narcotics and other controlled substances to the airline and security before handing over hold baggage.
Permit requirement: any product listed under national or international controlled-drugs schedules usually needs prior authorization from the competent authority in the country of departure, transit and arrival. Authorization types include personal import/export permits, controlled-drug licences, or medical exemptions; requirements differ by jurisdiction and by drug schedule (e.g., Schedule I versus Schedules II–V).
Standard documentation demanded for permit applications: passport copy, prescription details (active ingredient, dose, daily dosage, total quantity), clinical summary indicating treatment duration, travel itinerary, and contact details for the prescribing clinician. Permit processing times typically range from several days to several weeks; submit applications at least 2–4 weeks before travel when possible.
Quantity limits: many authorities restrict amounts to a treatment supply covering 30–90 days. Exceeding local limits will usually trigger a formal import licence requirement or refusal. Certain substances are prohibited outright by specific states (examples include cannabis products, codeine preparations, some stimulants); possession without an approved permit can result in seizure, fines, detention or criminal charges.
Transit rules: transit-state legislation can require prior clearance even if final destination has granted a permit. Always confirm rules for every country on the route; a permit valid for the destination might not cover airports located in a transit country that treats the drug as controlled.
How to obtain permits: identify the scheduling classification under origin, transit and destination laws; contact the national drug-control agency or national medicines regulator; follow the online application process where available; attach required clinical documents; keep copies of the permit and application confirmation in both printed and electronic forms.
Country / Region | Competent authority (examples) | Typical requirement | Processing time / common supply limit |
---|---|---|---|
United States | DEA; Customs and Border Protection (CBP) | Prior authorization may be required for certain controlled categories; declare at arrival | Days to weeks; many permits limit to a 30–90 day supply |
United Kingdom | Home Office (Controlled Drugs licensing); MHRA | Controlled Drugs import/export licences often required for Schedules 2–3 | Several working days to a few weeks; supply limits commonly applied |
Canada | Health Canada; Canada Border Services Agency | Prior notification or permit may be required for certain controlled substances | Variable; allow multiple days for processing |
Australia | Therapeutic Goods Administration; Department of Health | Personal import permits or authorisations required for many controlled drugs | Days to weeks; limits often tied to treatment duration (30–90 days) |
European Union / Schengen | National medicines agencies (each member state) | National import permits or certificates may be required; rules vary between states | Variable by member state; commonly up to 30–90 days’ supply |
Non-compliance consequences include seizure at security or customs, fines, criminal prosecution, refusal to board or denial of entry. Obtain written permit confirmations and store them separately from hold baggage records; confirm airline policy about transporting controlled drugs in hold compartments prior to travel.
How to transport temperature‑sensitive medicines (insulin, biologics) if forced to stow in aircraft hold
Keep insulin and biologic injectables at 2–8°C inside a validated insulated transport case with phase‑change packs designed to hold that range and an independent temperature data logger during the whole transit through the aircraft hold.
Use a hard‑sided insulated cooler (vacuum or foam lined) with certified PCM cold packs that maintain 2–8°C for the anticipated total time from airport drop‑off to arrival; avoid standard frozen gel packs unless manufacturer documentation explicitly permits freezing of that product.
Place the product in a sealed secondary waterproof container (rigid vial or resealable leakproof bag) surrounded by absorbent material to contain leaks. Include a manufacturer printout showing recommended storage temperature and lot numbers inside the inner container.
Fit a continuous electronic temperature logger (USB or Bluetooth) or at minimum a single‑use chemical time‑temperature indicator inside the inner container. Configure alert thresholds at 8°C and review records immediately on arrival; record duration outside target range and retain data for pharmacy/insurance claims if potency loss is suspected.
Position the insulated case in the middle of a hard‑shell suitcase or dedicated air cargo box, surrounded on all sides by clothing or foam padding; avoid placement next to external walls, wheels, base plates or hinges where transfer of heat/cold and mechanical stress are highest.
Dry ice may be used only after airline and handling‑agent approval. Typical passenger limits are about 2.5 kg per piece and require venting, UN1845 marking and declaration at bag drop; check the carrier and IATA/DG provisions for precise limits before using CO2 solid.
Prepare for delays: include spare phase‑change packs sized for the maximum expected delay, know the PCM hold time (hours at ambient 25–30°C), and have contact details for airport pharmacies or ground handling teams that can provide refrigerated storage on extended layovers.
Anticipate security inspection: pack so inner seals remain intact if opened; keep needles/syringes in original sealed packaging and include prescriber contact information and a concise physician statement inside the inner container to facilitate screening without destroying packaging.
Label external baggage tag clearly as “Temperature‑sensitive – contains prescription injectables” and request priority handling at bag drop so the item is stowed as centrally as possible. Keep a spare insulated kit and extra cold packs in carry‑on for transfers or unexpected retrieval.